STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1028 aa)    
Predicted Functional Partners:
BAZ1A
Bromodomain adjacent to zinc finger domain 1A.
    
 0.976
LOC102699233
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.967
pole3
Polymerase (DNA directed), epsilon 3 (p17 subunit).
    
 0.949
W5LY98_LEPOC
Bromodomain adjacent to zinc finger domain, 1B.
   
 0.933
W5N7Y2_LEPOC
Bromodomain PHD finger transcription factor.
   
 
 0.926
rsf1
Remodeling and spacing factor 1b, tandem duplicate 1.
   
 0.918
rbbp4
Retinoblastoma binding protein 4.
   
 0.909
rbbp7
Retinoblastoma binding protein 4, like.
   
 0.909
W5MJK0_LEPOC
Histone H2B; Belongs to the histone H2B family.
   
 0.892
W5NLL5_LEPOC
Histone H2B; Belongs to the histone H2B family.
   
 0.892
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.