STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5MS90_LEPOCPHD-type domain-containing protein. (135 aa)    
Predicted Functional Partners:
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.830
rbbp5
Retinoblastoma binding protein 5.
   
 0.824
rbbp4
Retinoblastoma binding protein 4.
   
 0.787
rbbp7
Retinoblastoma binding protein 4, like.
   
 0.787
suz12
SUZ12 polycomb repressive complex 2 subunit b.
   
 0.723
eed
Embryonic ectoderm development.
   
 0.713
W5MXZ9_LEPOC
M-phase phosphoprotein 8.
    
 0.702
W5MF61_LEPOC
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.655
LOC102699233
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.651
W5LWX1_LEPOC
C2H2-type domain-containing protein.
   
 0.637
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.