STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102695073Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (133 aa)    
Predicted Functional Partners:
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
    
 0.948
insr
Tyrosine-protein kinase receptor.
    
 0.943
igf1r
Tyrosine-protein kinase receptor.
    
 0.943
mst1r
Macrophage stimulating 1 receptor b.
   
 0.900
met
MET proto-oncogene, receptor tyrosine kinase.
   
 0.900
W5NLK8_LEPOC
Insulin receptor substrate 1.
     
 0.892
egf
Epidermal growth factor.
     
 0.888
W5LWR7_LEPOC
Peptidase_M16_M domain-containing protein.
    
 0.841
nrdc
Nardilysin b (N-arginine dibasic convertase); Belongs to the peptidase M16 family.
    
 0.841
W5NDH1_LEPOC
Insulin-like growth factor 1.
     
0.835
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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