STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102683457Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1961 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.997
scn1b
Sodium channel, voltage-gated, type I, beta b.
    
 0.985
LOC102686449
Si:ch211-225p5.8.
    
 0.978
scn4b
Sodium channel, voltage-gated, type IV, beta a.
    
 0.972
W5MIK6_LEPOC
Sodium channel, voltage-gated, type II, beta.
   
 0.958
W5M2W6_LEPOC
Sodium channel, voltage-gated, type III, beta.
    
 0.827
CALM1
Calmodulin 1; Belongs to the calmodulin family.
    
 0.805
calm1
Uncharacterized protein; Belongs to the calmodulin family.
    
 0.805
CALM2
Calmodulin 2; Belongs to the calmodulin family.
    
 0.805
cacna1h
Calcium channel, voltage-dependent, T type, alpha 1H subunit b.
   
0.790
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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