STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5MUY9_LEPOCSterile alpha motif domain containing 1b. (642 aa)    
Predicted Functional Partners:
W5MQE4_LEPOC
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
   
 0.930
meaf6
MYST/Esa1-associated factor 6.
    
 0.929
LOC102699233
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.915
W5M4H6_LEPOC
DNA methyltransferase 1 associated protein 1.
   
 0.894
ruvbl1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
   
 0.888
W5MZ00_LEPOC
Bromodomain and PHD finger containing, 3a.
   
 0.817
W5NB67_LEPOC
Uncharacterized protein.
   
 0.805
brd1
Bromodomain containing 1a.
   
 0.805
epc2
Enhancer of polycomb homolog.
    
 0.804
W5MJV7_LEPOC
Enhancer of polycomb homolog.
    
 0.804
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.