STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRAG1PEAK1 related, kinase-activating pseudokinase 1. (1253 aa)    
Predicted Functional Partners:
itsn2
Intersectin 2b.
     
 0.709
fam20a
FAM20A golgi associated secretory pathway pseudokinase.
      
 0.587
itsn1
Intersectin 1 (SH3 domain protein).
     
 0.582
W5MQE4_LEPOC
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
      
 0.534
nck1
Cytoplasmic protein.
    
  0.435
nck2
Cytoplasmic protein.
    
  0.435
grap
GRB2 related adaptor protein b.
    
 0.429
grap2
GRB2 related adaptor protein 2a.
    
 0.429
grb2
Growth factor receptor-bound protein 2b.
    
 0.429
gja5
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.428
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.