W5MX10_LEPOC protein (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

W5MX10_LEPOC

Malate synthase-like. (550 aa)

Predicted Functional Partners:

cs

0.983

W5MSQ5_LEPOC

0.956

mdh2

0.951

W5MM14_LEPOC

0.951

W5N0W0_LEPOC

0.951

suclg1

0.950

agxt

0.950

W5M1K4_LEPOC

0.945

l2hgdh

0.939

acaa1

0.937

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W5M1K4_LEPOC	W5MM14_LEPOC	ENSLOCP00000002262	ENSLOCP00000009423	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Si:dkey-31b16.7.	0.935
W5M1K4_LEPOC	W5MSQ5_LEPOC	ENSLOCP00000002262	ENSLOCP00000011414	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Succinate dehydrogenase complex, subunit A, flavoprotein (Fp).	0.938
W5M1K4_LEPOC	W5MX10_LEPOC	ENSLOCP00000002262	ENSLOCP00000012919	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate synthase-like.	0.945
W5M1K4_LEPOC	W5N0W0_LEPOC	ENSLOCP00000002262	ENSLOCP00000014269	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Aconitase 2, mitochondrial.	0.759
W5M1K4_LEPOC	acaa1	ENSLOCP00000002262	ENSLOCP00000011938	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.695
W5M1K4_LEPOC	cs	ENSLOCP00000002262	ENSLOCP00000005579	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Citrate synthase; Belongs to the citrate synthase family.	0.964
W5M1K4_LEPOC	l2hgdh	ENSLOCP00000002262	ENSLOCP00000014555	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	L-2-hydroxyglutarate dehydrogenase.	0.941
W5M1K4_LEPOC	mdh2	ENSLOCP00000002262	ENSLOCP00000001970	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.956
W5M1K4_LEPOC	suclg1	ENSLOCP00000002262	ENSLOCP00000003035	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.938
W5MM14_LEPOC	W5M1K4_LEPOC	ENSLOCP00000009423	ENSLOCP00000002262	Si:dkey-31b16.7.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.935
W5MM14_LEPOC	W5MSQ5_LEPOC	ENSLOCP00000009423	ENSLOCP00000011414	Si:dkey-31b16.7.	Succinate dehydrogenase complex, subunit A, flavoprotein (Fp).	0.999
W5MM14_LEPOC	W5MX10_LEPOC	ENSLOCP00000009423	ENSLOCP00000012919	Si:dkey-31b16.7.	Malate synthase-like.	0.951
W5MM14_LEPOC	W5N0W0_LEPOC	ENSLOCP00000009423	ENSLOCP00000014269	Si:dkey-31b16.7.	Aconitase 2, mitochondrial.	0.936
W5MM14_LEPOC	acaa1	ENSLOCP00000009423	ENSLOCP00000011938	Si:dkey-31b16.7.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.789
W5MM14_LEPOC	cs	ENSLOCP00000009423	ENSLOCP00000005579	Si:dkey-31b16.7.	Citrate synthase; Belongs to the citrate synthase family.	0.997
W5MM14_LEPOC	l2hgdh	ENSLOCP00000009423	ENSLOCP00000014555	Si:dkey-31b16.7.	L-2-hydroxyglutarate dehydrogenase.	0.752
W5MM14_LEPOC	mdh2	ENSLOCP00000009423	ENSLOCP00000001970	Si:dkey-31b16.7.	Malate dehydrogenase.	0.977
W5MM14_LEPOC	suclg1	ENSLOCP00000009423	ENSLOCP00000003035	Si:dkey-31b16.7.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.997
W5MSQ5_LEPOC	W5M1K4_LEPOC	ENSLOCP00000011414	ENSLOCP00000002262	Succinate dehydrogenase complex, subunit A, flavoprotein (Fp).	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.938
W5MSQ5_LEPOC	W5MM14_LEPOC	ENSLOCP00000011414	ENSLOCP00000009423	Succinate dehydrogenase complex, subunit A, flavoprotein (Fp).	Si:dkey-31b16.7.	0.999