STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5MY45_LEPOCZinc finger, MYM-type 2. (1180 aa)    
Predicted Functional Partners:
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 
 0.691
mst1r
Macrophage stimulating 1 receptor b.
    
  0.528
met
MET proto-oncogene, receptor tyrosine kinase.
    
  0.528
ptk7
Protein tyrosine kinase 7a; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.522
ripk4
Receptor-interacting serine-threonine kinase 4.
   
  0.504
W5MSM4_LEPOC
Protein kinase domain-containing protein.
   
  0.504
LOC102693234
Fras1 related extracellular matrix 1b.
    
 0.501
frem1
Fras1 related extracellular matrix 1a.
    
 0.501
pgbd5
PiggyBac transposable element derived 5.
    
 
 0.492
W5MSQ6_LEPOC
AT rich interactive domain 4A (RBP1-like).
   
 0.488
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.