sem1 protein (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

sem1

SEM1 26S proteasome complex subunit. (70 aa)

Predicted Functional Partners:

psmd14

0.996

W5MNK3_LEPOC

0.995

psmd3

0.995

psmd6

0.993

psmd7

0.984

psmd11

0.984

psmd12

0.984

W5NA30_LEPOC

0.984

psmd2

0.983

psmd1

0.981

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W5MNK3_LEPOC	psmd14	ENSLOCP00000009962	ENSLOCP00000010457	Tower domain-containing protein.	Proteasome 26S subunit, non-ATPase 14.	0.412
W5MNK3_LEPOC	psmd3	ENSLOCP00000009962	ENSLOCP00000015871	Tower domain-containing protein.	Proteasome 26S subunit, non-ATPase 3.	0.453
W5MNK3_LEPOC	sem1	ENSLOCP00000009962	ENSLOCP00000013499	Tower domain-containing protein.	SEM1 26S proteasome complex subunit.	0.995
W5NA30_LEPOC	psmd1	ENSLOCP00000017489	ENSLOCP00000005617	Proteasome 26S subunit, non-ATPase 8.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.998
W5NA30_LEPOC	psmd11	ENSLOCP00000017489	ENSLOCP00000015953	Proteasome 26S subunit, non-ATPase 8.	Proteasome 26S subunit, non-ATPase 11b.	0.999
W5NA30_LEPOC	psmd12	ENSLOCP00000017489	ENSLOCP00000016782	Proteasome 26S subunit, non-ATPase 8.	Proteasome 26S subunit, non-ATPase 12.	0.999
W5NA30_LEPOC	psmd14	ENSLOCP00000017489	ENSLOCP00000010457	Proteasome 26S subunit, non-ATPase 8.	Proteasome 26S subunit, non-ATPase 14.	0.999
W5NA30_LEPOC	psmd2	ENSLOCP00000017489	ENSLOCP00000010610	Proteasome 26S subunit, non-ATPase 8.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
W5NA30_LEPOC	psmd3	ENSLOCP00000017489	ENSLOCP00000015871	Proteasome 26S subunit, non-ATPase 8.	Proteasome 26S subunit, non-ATPase 3.	0.998
W5NA30_LEPOC	psmd6	ENSLOCP00000017489	ENSLOCP00000012638	Proteasome 26S subunit, non-ATPase 8.	Proteasome 26S subunit, non-ATPase 6.	0.999
W5NA30_LEPOC	psmd7	ENSLOCP00000017489	ENSLOCP00000004742	Proteasome 26S subunit, non-ATPase 8.	Proteasome 26S subunit, non-ATPase 7.	0.999
W5NA30_LEPOC	sem1	ENSLOCP00000017489	ENSLOCP00000013499	Proteasome 26S subunit, non-ATPase 8.	SEM1 26S proteasome complex subunit.	0.984
psmd1	W5NA30_LEPOC	ENSLOCP00000005617	ENSLOCP00000017489	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 8.	0.998
psmd1	psmd11	ENSLOCP00000005617	ENSLOCP00000015953	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 11b.	0.999
psmd1	psmd12	ENSLOCP00000005617	ENSLOCP00000016782	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 12.	0.999
psmd1	psmd14	ENSLOCP00000005617	ENSLOCP00000010457	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 14.	0.999
psmd1	psmd2	ENSLOCP00000005617	ENSLOCP00000010610	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
psmd1	psmd3	ENSLOCP00000005617	ENSLOCP00000015871	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 3.	0.999
psmd1	psmd6	ENSLOCP00000005617	ENSLOCP00000012638	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 6.	0.999
psmd1	psmd7	ENSLOCP00000005617	ENSLOCP00000004742	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 7.	0.999