egf protein (Lepisosteus oculatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

egf

Epidermal growth factor. (1204 aa)

Predicted Functional Partners:

W5N0P5_LEPOC

0.976

erbb2

0.974

W5M7P2_LEPOC

0.945

W5MAN3_LEPOC

0.945

tgfa

0.938

pdgfrb

0.929

W5N848_LEPOC

0.906

vegfa

0.902

igf1r

0.896

insr

0.893

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W5M7P2_LEPOC	W5N848_LEPOC	ENSLOCP00000004400	ENSLOCP00000016807	Erb-b2 receptor tyrosine kinase 3b.	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.791
W5M7P2_LEPOC	egf	ENSLOCP00000004400	ENSLOCP00000014477	Erb-b2 receptor tyrosine kinase 3b.	Epidermal growth factor.	0.945
W5M7P2_LEPOC	erbb2	ENSLOCP00000004400	ENSLOCP00000015640	Erb-b2 receptor tyrosine kinase 3b.	Receptor protein-tyrosine kinase.	0.834
W5M7P2_LEPOC	igf1r	ENSLOCP00000004400	ENSLOCP00000017791	Erb-b2 receptor tyrosine kinase 3b.	Tyrosine-protein kinase receptor.	0.654
W5M7P2_LEPOC	insr	ENSLOCP00000004400	ENSLOCP00000005036	Erb-b2 receptor tyrosine kinase 3b.	Tyrosine-protein kinase receptor.	0.654
W5M7P2_LEPOC	pdgfrb	ENSLOCP00000004400	ENSLOCP00000013637	Erb-b2 receptor tyrosine kinase 3b.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.778
W5M7P2_LEPOC	tgfa	ENSLOCP00000004400	ENSLOCP00000019283	Erb-b2 receptor tyrosine kinase 3b.	Transforming growth factor, alpha.	0.930
W5M7P2_LEPOC	vegfa	ENSLOCP00000004400	ENSLOCP00000019712	Erb-b2 receptor tyrosine kinase 3b.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.745
W5MAN3_LEPOC	W5N848_LEPOC	ENSLOCP00000005442	ENSLOCP00000016807	Receptor protein-tyrosine kinase.	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.791
W5MAN3_LEPOC	egf	ENSLOCP00000005442	ENSLOCP00000014477	Receptor protein-tyrosine kinase.	Epidermal growth factor.	0.945
W5MAN3_LEPOC	erbb2	ENSLOCP00000005442	ENSLOCP00000015640	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.826
W5MAN3_LEPOC	igf1r	ENSLOCP00000005442	ENSLOCP00000017791	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.654
W5MAN3_LEPOC	insr	ENSLOCP00000005442	ENSLOCP00000005036	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.654
W5MAN3_LEPOC	pdgfrb	ENSLOCP00000005442	ENSLOCP00000013637	Receptor protein-tyrosine kinase.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.778
W5MAN3_LEPOC	tgfa	ENSLOCP00000005442	ENSLOCP00000019283	Receptor protein-tyrosine kinase.	Transforming growth factor, alpha.	0.930
W5MAN3_LEPOC	vegfa	ENSLOCP00000005442	ENSLOCP00000019712	Receptor protein-tyrosine kinase.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.745
W5N0P5_LEPOC	W5N848_LEPOC	ENSLOCP00000014204	ENSLOCP00000016807	Receptor protein-tyrosine kinase.	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.862
W5N0P5_LEPOC	egf	ENSLOCP00000014204	ENSLOCP00000014477	Receptor protein-tyrosine kinase.	Epidermal growth factor.	0.976
W5N0P5_LEPOC	erbb2	ENSLOCP00000014204	ENSLOCP00000015640	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.866
W5N0P5_LEPOC	igf1r	ENSLOCP00000014204	ENSLOCP00000017791	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.654