STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5N2I0_LEPOCFAD-dependent oxidoreductase domain containing 2. (606 aa)    
Predicted Functional Partners:
W5N6B6_LEPOC
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
    
 
 0.789
txn2
Thioredoxin 2.
  
 
 0.740
txndc16
Thioredoxin domain containing 16.
   
 
 0.691
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
  
 0.675
atp5pb
ATP synthase peripheral stalk-membrane subunit b.
   
   0.640
metap1d
Methionyl aminopeptidase type 1D (mitochondrial); Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 0.632
atp5f1a
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
   0.628
SEL1L2
SEL1L2 adaptor subunit of ERAD E3 ligase.
    
 
 0.624
W5NJ40_LEPOC
Epoxide hydrolase 2, cytoplasmic.
  
 0.622
coq6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
  
 0.602
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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