dyrk3 protein (Lepisosteus oculatus) - STRING interaction network

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Score

dyrk3

Dual specificity tyrosine phosphorylation regulated kinase 3. (581 aa)

Predicted Functional Partners:

dcaf7

0.770

tp53

0.761

W5LZK6_LEPOC

0.701

pin1

0.610

DCAF1

0.606

W5NH41_LEPOC

0.604

plk3

0.595

PLK1

0.595

plk2

0.595

rps27a

0.567

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCAF1	dyrk3	ENSLOCP00000016618	ENSLOCP00000015054	DDB1 and CUL4 associated factor 1.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.606
PLK1	dyrk3	ENSLOCP00000006824	ENSLOCP00000015054	Serine/threonine-protein kinase PLK.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.595
PLK1	rps27a	ENSLOCP00000006824	ENSLOCP00000019146	Serine/threonine-protein kinase PLK.	Ribosomal protein S27a.	0.695
PLK1	tp53	ENSLOCP00000006824	ENSLOCP00000017063	Serine/threonine-protein kinase PLK.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.764
W5LZK6_LEPOC	W5NH41_LEPOC	ENSLOCP00000001563	ENSLOCP00000019950	Non-specific serine/threonine protein kinase.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.909
W5LZK6_LEPOC	dyrk3	ENSLOCP00000001563	ENSLOCP00000015054	Non-specific serine/threonine protein kinase.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.701
W5LZK6_LEPOC	rps27a	ENSLOCP00000001563	ENSLOCP00000019146	Non-specific serine/threonine protein kinase.	Ribosomal protein S27a.	0.666
W5LZK6_LEPOC	tp53	ENSLOCP00000001563	ENSLOCP00000017063	Non-specific serine/threonine protein kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.996
W5NH41_LEPOC	W5LZK6_LEPOC	ENSLOCP00000019950	ENSLOCP00000001563	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	Non-specific serine/threonine protein kinase.	0.909
W5NH41_LEPOC	dyrk3	ENSLOCP00000019950	ENSLOCP00000015054	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.604
W5NH41_LEPOC	rps27a	ENSLOCP00000019950	ENSLOCP00000019146	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	Ribosomal protein S27a.	0.976
W5NH41_LEPOC	tp53	ENSLOCP00000019950	ENSLOCP00000017063	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.998
dcaf7	dyrk3	ENSLOCP00000014572	ENSLOCP00000015054	Ddb1 and cul4 associated factor 7.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.770
dyrk3	DCAF1	ENSLOCP00000015054	ENSLOCP00000016618	Dual specificity tyrosine phosphorylation regulated kinase 3.	DDB1 and CUL4 associated factor 1.	0.606
dyrk3	PLK1	ENSLOCP00000015054	ENSLOCP00000006824	Dual specificity tyrosine phosphorylation regulated kinase 3.	Serine/threonine-protein kinase PLK.	0.595
dyrk3	W5LZK6_LEPOC	ENSLOCP00000015054	ENSLOCP00000001563	Dual specificity tyrosine phosphorylation regulated kinase 3.	Non-specific serine/threonine protein kinase.	0.701
dyrk3	W5NH41_LEPOC	ENSLOCP00000015054	ENSLOCP00000019950	Dual specificity tyrosine phosphorylation regulated kinase 3.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.604
dyrk3	dcaf7	ENSLOCP00000015054	ENSLOCP00000014572	Dual specificity tyrosine phosphorylation regulated kinase 3.	Ddb1 and cul4 associated factor 7.	0.770
dyrk3	pin1	ENSLOCP00000015054	ENSLOCP00000008762	Dual specificity tyrosine phosphorylation regulated kinase 3.	Peptidyl-prolyl cis-trans isomerase.	0.610
dyrk3	plk2	ENSLOCP00000015054	ENSLOCP00000009231	Dual specificity tyrosine phosphorylation regulated kinase 3.	Serine/threonine-protein kinase PLK.	0.595