STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC4SHC adaptor protein 4. (610 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
 0.938
mst1r
Macrophage stimulating 1 receptor b.
   
 0.910
met
MET proto-oncogene, receptor tyrosine kinase.
   
 0.910
W5MRF2_LEPOC
GRB2-associated binding protein 1.
    
 0.904
sos2
Son of sevenless homolog 2 (Drosophila).
    
 0.894
pdgfrb
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.892
LOC102686356
Tyrosine-protein kinase.
    
 0.890
epha2
Eph receptor A2 b.
   
  0.883
LOC102694942
TYRO3 protein tyrosine kinase.
    
 0.883
W5MM02_LEPOC
Inositol polyphosphate phosphatase-like 1a.
    
 0.877
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.