STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cenpuUncharacterized protein. (465 aa)    
Predicted Functional Partners:
W5NBB2_LEPOC
X-linked inhibitor of apoptosis.
   
 0.943
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 0.915
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.909
W5LX96_LEPOC
Centromere protein N.
   
 0.903
birc2
Baculoviral IAP repeat containing 2.
   
 0.897
W5N6Z1_LEPOC
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.887
W5N8W0_LEPOC
Uncharacterized protein.
   
 0.887
W5NEG4_LEPOC
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.887
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.882
W5NDY1_LEPOC
Centromere protein I.
   
 0.879
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.