STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5N9V2_LEPOCIntegrase catalytic domain-containing protein. (537 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
    
 0.929
W5MJC8_LEPOC
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
   
 
 0.730
rpa1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.602
lin52
Lin-52 DREAM MuvB core complex component.
    
 0.573
lin54
Lin-54 DREAM MuvB core complex component.
    
 0.564
lin9
Lin-9 DREAM MuvB core complex component.
    
 0.556
rpa2
Replication protein A2.
   
 0.543
W5NNW9_LEPOC
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.543
W5NNB8_LEPOC
RT_RNaseH_2 domain-containing protein.
 
     0.537
W5NL88_LEPOC
Uncharacterized protein.
 
     0.532
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.