STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1262 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
 0.961
W5MLW0_LEPOC
Protein tyrosine kinase 2aa.
    
 0.906
hras
HRas proto-oncogene, GTPase a.
    
 0.904
nras
NRAS proto-oncogene, GTPase.
    
 0.904
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
    
 0.904
mras
Muscle RAS oncogene homolog.
    
 0.903
rras2
RAS related 2.
    
 0.903
cacng7
Calcium channel, voltage-dependent, gamma subunit 7a.
    
  0.865
cacng4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
  0.865
cacng5
Calcium channel, voltage-dependent, gamma subunit 5a.
    
  0.865
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.