STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NDQ7_LEPOCCyclin and CBS domain divalent metal cation transport mediator 4b. (786 aa)    
Predicted Functional Partners:
gmps
Guanine monophosphate synthase.
  
 
 0.809
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
    
 0.751
LOC102692060
Uncharacterized protein; Belongs to the 5'-nucleotidase family.
    
 0.665
W5NJV3_LEPOC
5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.
    
 0.665
itpa
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
    
  0.661
ptp4a3
Protein tyrosine phosphatase 4A3b.
    
 
 0.648
ptp4a2
Protein tyrosine phosphatase 4A2b.
    
 
 0.594
ptp4a1
Protein tyrosine phosphatase 4A1.
    
 
 0.594
W5NJ40_LEPOC
Epoxide hydrolase 2, cytoplasmic.
  
 
  0.547
aprt
Adenine phosphoribosyltransferase.
  
 
 0.545
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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