node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HDAC2 | KDM1B | ENSLOCP00000020985 | ENSLOCP00000007127 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine demethylase 1B. | 0.768 |
HDAC2 | LOC102691383 | ENSLOCP00000020985 | ENSLOCP00000019853 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amine oxidase. | 0.768 |
HDAC2 | MAOA | ENSLOCP00000020985 | ENSLOCP00000016990 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amine oxidase. | 0.768 |
HDAC2 | W5M1R1_LEPOC | ENSLOCP00000020985 | ENSLOCP00000002319 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amine oxidase. | 0.768 |
HDAC2 | W5MGB7_LEPOC | ENSLOCP00000020985 | ENSLOCP00000007426 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | High mobility group 20B. | 0.849 |
HDAC2 | W5MSQ6_LEPOC | ENSLOCP00000020985 | ENSLOCP00000011415 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | AT rich interactive domain 4A (RBP1-like). | 0.998 |
HDAC2 | W5NEW9_LEPOC | ENSLOCP00000020985 | ENSLOCP00000019178 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Uncharacterized protein. | 0.834 |
HDAC2 | W5NG20_LEPOC | ENSLOCP00000020985 | ENSLOCP00000019579 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Translocase of outer mitochondrial membrane 20. | 0.998 |
HDAC2 | hdac1 | ENSLOCP00000020985 | ENSLOCP00000002993 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.857 |
HDAC2 | kdm1a | ENSLOCP00000020985 | ENSLOCP00000005363 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.938 |
KDM1B | HDAC2 | ENSLOCP00000007127 | ENSLOCP00000020985 | Lysine demethylase 1B. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.768 |
KDM1B | W5MGB7_LEPOC | ENSLOCP00000007127 | ENSLOCP00000007426 | Lysine demethylase 1B. | High mobility group 20B. | 0.487 |
KDM1B | W5MSQ6_LEPOC | ENSLOCP00000007127 | ENSLOCP00000011415 | Lysine demethylase 1B. | AT rich interactive domain 4A (RBP1-like). | 0.686 |
KDM1B | W5NEW9_LEPOC | ENSLOCP00000007127 | ENSLOCP00000019178 | Lysine demethylase 1B. | Uncharacterized protein. | 0.845 |
KDM1B | W5NG20_LEPOC | ENSLOCP00000007127 | ENSLOCP00000019579 | Lysine demethylase 1B. | Translocase of outer mitochondrial membrane 20. | 0.686 |
KDM1B | hdac1 | ENSLOCP00000007127 | ENSLOCP00000002993 | Lysine demethylase 1B. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.768 |
KDM1B | kdm1a | ENSLOCP00000007127 | ENSLOCP00000005363 | Lysine demethylase 1B. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.782 |
LOC102691383 | HDAC2 | ENSLOCP00000019853 | ENSLOCP00000020985 | Amine oxidase. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.768 |
LOC102691383 | MAOA | ENSLOCP00000019853 | ENSLOCP00000016990 | Amine oxidase. | Amine oxidase. | 0.833 |
LOC102691383 | W5M1R1_LEPOC | ENSLOCP00000019853 | ENSLOCP00000002319 | Amine oxidase. | Amine oxidase. | 0.873 |