cdc123 protein (Lepisosteus oculatus) - STRING interaction network

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cdc123

Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family. (342 aa)

Predicted Functional Partners:

eif2s3

0.966

eefsec

0.921

eif2s2

0.910

cops5

0.693

clg27h11orf58

0.689

mrps17

0.686

nudt5

0.616

wdfy2

0.539

RNF8

0.493

eif2s1

0.489

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RNF8	cdc123	ENSLOCP00000020254	ENSLOCP00000019344	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.493
RNF8	nudt5	ENSLOCP00000020254	ENSLOCP00000019342	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.	0.493
cdc123	RNF8	ENSLOCP00000019344	ENSLOCP00000020254	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.493
cdc123	clg27h11orf58	ENSLOCP00000019344	ENSLOCP00000003591	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Zgc:56106.	0.689
cdc123	cops5	ENSLOCP00000019344	ENSLOCP00000005487	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	COP9 signalosome subunit 5.	0.693
cdc123	eefsec	ENSLOCP00000019344	ENSLOCP00000017891	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Eukaryotic elongation factor, selenocysteine-tRNA-specific.	0.921
cdc123	eif2s1	ENSLOCP00000019344	ENSLOCP00000017450	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Eukaryotic translation initiation factor 2, subunit 1 alpha a.	0.489
cdc123	eif2s2	ENSLOCP00000019344	ENSLOCP00000008719	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Eukaryotic translation initiation factor 2, subunit 2 beta.	0.910
cdc123	eif2s3	ENSLOCP00000019344	ENSLOCP00000003988	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.966
cdc123	mrps17	ENSLOCP00000019344	ENSLOCP00000004924	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Mitochondrial ribosomal protein S17.	0.686
cdc123	nudt5	ENSLOCP00000019344	ENSLOCP00000019342	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.	0.616
cdc123	wdfy2	ENSLOCP00000019344	ENSLOCP00000012682	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	WD repeat and FYVE domain containing 2.	0.539
clg27h11orf58	cdc123	ENSLOCP00000003591	ENSLOCP00000019344	Zgc:56106.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.689
cops5	cdc123	ENSLOCP00000005487	ENSLOCP00000019344	COP9 signalosome subunit 5.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.693
cops5	eefsec	ENSLOCP00000005487	ENSLOCP00000017891	COP9 signalosome subunit 5.	Eukaryotic elongation factor, selenocysteine-tRNA-specific.	0.651
cops5	eif2s1	ENSLOCP00000005487	ENSLOCP00000017450	COP9 signalosome subunit 5.	Eukaryotic translation initiation factor 2, subunit 1 alpha a.	0.835
cops5	eif2s2	ENSLOCP00000005487	ENSLOCP00000008719	COP9 signalosome subunit 5.	Eukaryotic translation initiation factor 2, subunit 2 beta.	0.744
cops5	eif2s3	ENSLOCP00000005487	ENSLOCP00000003988	COP9 signalosome subunit 5.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.651
eefsec	cdc123	ENSLOCP00000017891	ENSLOCP00000019344	Eukaryotic elongation factor, selenocysteine-tRNA-specific.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.921
eefsec	cops5	ENSLOCP00000017891	ENSLOCP00000005487	Eukaryotic elongation factor, selenocysteine-tRNA-specific.	COP9 signalosome subunit 5.	0.651