STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NFL1_LEPOCDEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57. (1431 aa)    
Predicted Functional Partners:
itsn2
Intersectin 2b.
   
  0.992
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.894
itsn1
Intersectin 1 (SH3 domain protein).
   
  0.873
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.826
utp14a
UTP14C small subunit processome component.
   
 0.825
noc4l
Nucleolar complex associated 4 homolog.
   
  0.802
UTP18
UTP18 small subunit processome component.
   
 0.799
W5LZV8_LEPOC
UTP3 small subunit processome component.
   
 0.792
slu7
SLU7 homolog, splicing factor.
    
 0.784
W5NAT9_LEPOC
WD repeat domain 46.
   
 0.784
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.