node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OGDH | SUCLA2 | ENSLOCP00000018819 | ENSLOCP00000012787 | Oxoglutarate dehydrogenase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.992 |
OGDH | bckdha | ENSLOCP00000018819 | ENSLOCP00000017509 | Oxoglutarate dehydrogenase. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.922 |
OGDH | bckdhb | ENSLOCP00000018819 | ENSLOCP00000021087 | Oxoglutarate dehydrogenase. | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.926 |
OGDH | dbt | ENSLOCP00000018819 | ENSLOCP00000000326 | Oxoglutarate dehydrogenase. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.977 |
OGDH | dlat | ENSLOCP00000018819 | ENSLOCP00000001728 | Oxoglutarate dehydrogenase. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.983 |
OGDH | dld | ENSLOCP00000018819 | ENSLOCP00000019577 | Oxoglutarate dehydrogenase. | Dihydrolipoyl dehydrogenase. | 0.998 |
OGDH | dlst | ENSLOCP00000018819 | ENSLOCP00000013103 | Oxoglutarate dehydrogenase. | Dihydrolipoamide S-succinyltransferase. | 0.999 |
OGDH | pdha1 | ENSLOCP00000018819 | ENSLOCP00000004156 | Oxoglutarate dehydrogenase. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.921 |
OGDH | pdhb | ENSLOCP00000018819 | ENSLOCP00000016253 | Oxoglutarate dehydrogenase. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.916 |
OGDH | pdhx | ENSLOCP00000018819 | ENSLOCP00000001547 | Oxoglutarate dehydrogenase. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.982 |
SUCLA2 | OGDH | ENSLOCP00000012787 | ENSLOCP00000018819 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Oxoglutarate dehydrogenase. | 0.992 |
SUCLA2 | bckdha | ENSLOCP00000012787 | ENSLOCP00000017509 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.835 |
SUCLA2 | bckdhb | ENSLOCP00000012787 | ENSLOCP00000021087 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.826 |
SUCLA2 | dbt | ENSLOCP00000012787 | ENSLOCP00000000326 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.898 |
SUCLA2 | dlat | ENSLOCP00000012787 | ENSLOCP00000001728 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.973 |
SUCLA2 | dld | ENSLOCP00000012787 | ENSLOCP00000019577 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Dihydrolipoyl dehydrogenase. | 0.993 |
SUCLA2 | dlst | ENSLOCP00000012787 | ENSLOCP00000013103 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Dihydrolipoamide S-succinyltransferase. | 0.987 |
SUCLA2 | pdha1 | ENSLOCP00000012787 | ENSLOCP00000004156 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.758 |
SUCLA2 | pdhb | ENSLOCP00000012787 | ENSLOCP00000016253 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.949 |
SUCLA2 | pdhx | ENSLOCP00000012787 | ENSLOCP00000001547 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.959 |