STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)    
Predicted Functional Partners:
LOC102688480
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.919
LOC102686398
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.919
LOC102686598
Uncharacterized protein.
    
 0.919
LOC102688820
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.911
W5NDZ4_LEPOC
Inositol 1,4,5-trisphosphate receptor, type 2.
    
 0.890
DGKQ
Diacylglycerol kinase.
     
 0.884
GNAO1
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.
   
 0.875
gnai2
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
   
 0.875
LOC102690587
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
   
 0.875
GNAI1
G protein subunit alpha i1.
   
 0.875
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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