STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
map3k7Mitogen-activated protein kinase kinase kinase 7. (653 aa)    
Predicted Functional Partners:
W5LYQ5_LEPOC
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.996
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.996
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
   
 0.995
map2k4
Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.
    
0.992
ube2n
Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.985
W5MIV7_LEPOC
Death domain-containing protein.
   
 0.981
W5M7V9_LEPOC
Uncharacterized protein.
    
 0.979
W5NF13_LEPOC
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.975
W5NK53_LEPOC
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.973
map2k6
Mitogen-activated protein kinase kinase 6.
   
0.970
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.