STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NLL5_LEPOCHistone H2B; Belongs to the histone H2B family. (115 aa)    
Predicted Functional Partners:
LOC102699233
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 0.999
leo1
Uncharacterized protein.
    
 0.998
LOC102694187
Histone H2A; Belongs to the histone H2A family.
 
 0.996
LOC102698545
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
 
 
 0.981
LOC102691803
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
 
 
 0.981
LOC102686492
Histone H2A; Belongs to the histone H2A family.
 
 0.977
H3-3B
Histone H3; Belongs to the histone H3 family.
 
 
 0.976
LOC102684155-2
Histone H3.3.
 
 
 0.976
LOC102684155
Histone H3; Belongs to the histone H3 family.
 
 
 0.975
LOC102696298
Histone H3; Belongs to the histone H3 family.
 
 
 0.970
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.