STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NMK9_LEPOCZmp:0000000735. (1413 aa)    
Predicted Functional Partners:
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.906
W5N6Z1_LEPOC
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.887
W5NEG4_LEPOC
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.887
birc6
Baculoviral IAP repeat containing 6.
   
 0.781
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.684
W5LX96_LEPOC
Centromere protein N.
   
 0.625
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.624
W5MSM4_LEPOC
Protein kinase domain-containing protein.
    
 0.624
W5N5W0_LEPOC
Uncharacterized protein.
    
 0.604
LOC102685547
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
 0.594
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.