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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000002445SMEK homolog 1, suppressor of mek1 (Dictyostelium). (817 aa)    
Predicted Functional Partners:
ENSCHAP00000036290
Protein phosphatase 4, catalytic subunit b.
   
 0.998
ptpa
Protein phosphatase 2 phosphatase activator.
    
 0.996
ENSCHAP00000053382
Protein phosphatase 4, regulatory subunit 2a.
   
 0.995
ppp4r2
Protein phosphatase 4 regulatory subunit 2.
   
 0.995
ppp6c
Protein phosphatase 6 catalytic subunit.
   
 0.976
igbp1
Immunoglobulin binding protein 1.
    
 0.961
ppp2cb
Protein phosphatase 2 catalytic subunit beta.
   
 0.947
ppp2ca
Protein phosphatase 2 catalytic subunit alpha.
   
 0.947
ENSCHAP00000029157
Protein phosphatase 2, regulatory subunit B, delta.
     
 0.926
PPP3CA
Protein phosphatase 3 catalytic subunit alpha.
   
 0.897
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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