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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hif1anHypoxia inducible factor 1 subunit alpha inhibitor. (354 aa)    
Predicted Functional Partners:
hif1a
Hypoxia inducible factor 1 subunit alpha.
    
 0.904
LOC105909740
Hypoxia-inducible factor 1-alpha-like.
    
 0.904
epas1
Endothelial PAS domain protein 1.
    
 0.904
ENSCHAP00000050928
annotation not available
    
 0.904
ENSCHAP00000051583
annotation not available
    
 0.904
notch1
Notch receptor 1.
    
 
 0.870
ENSCHAP00000062382
annotation not available
    
 
 0.870
ENSCHAP00000047986
Transient receptor potential cation channel, subfamily A, member 1b.
    
   0.850
ENSCHAP00000060816
Transient receptor potential cation channel, subfamily A, member 1a.
    
   0.850
ENSCHAP00000007229
annotation not available
    
 
 0.760
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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