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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105902263Dickkopf-related protein 1-like. (275 aa)    
Predicted Functional Partners:
lrp6
LDL receptor related protein 6.
    
 0.963
lrp5
LDL receptor related protein 5.
    
 0.963
ENSCHAP00000008128
Kringle containing transmembrane protein 1.
    
 0.952
wnt1
Wnt family member 1.
    
 0.905
ENSCHAP00000013590
annotation not available
  
  
0.891
wnt6
Wnt family member 6.
    
 0.891
ENSCHAP00000055564
Wingless-type MMTV integration site family, member 5a.
    
 0.876
wnt4
Wnt family member 4.
    
 0.873
ENSCHAP00000004318
Wingless-type MMTV integration site family, member 16.
    
 0.872
wnt8b
Wnt family member 8B.
    
 0.868
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.