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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000003678Down syndrome cell adhesion molecule like 1. (1276 aa)    
Predicted Functional Partners:
ENSCHAP00000012913
Netrin 2.
   
 0.739
LOC105898875
Netrin-1-like.
   
 0.739
ENSCHAP00000037175
Netrin 1a.
   
 0.739
ENSCHAP00000057801
Netrin 5.
   
 0.739
ENSCHAP00000047763
DCC netrin 1 receptor.
   
0.715
neo1
Neogenin 1.
   
0.715
ENSCHAP00000041250
Immunoglobulin superfamily, DCC subclass, member 4.
    
0.696
ENSCHAP00000009243
annotation not available
   
 0.641
ENSCHAP00000030067
P21 protein (Cdc42/Rac)-activated kinase 1.
   
 0.641
pak2
P21 (RAC1) activated kinase 2.
   
 0.633
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.