close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
herpud1Homocysteine inducible ER protein with ubiquitin like domain 1. (417 aa)    
Predicted Functional Partners:
ENSCHAP00000052133
Synovial apoptosis inhibitor 1, synoviolin.
   
 
 0.577
ENSCHAP00000001290
Autocrine motility factor receptor a.
   
 
 0.560
ENSCHAP00000056547
Activating transcription factor 4a.
   
 
 0.541
ENSCHAP00000043611
Activating transcription factor 4b.
   
 
 0.488
ENSCHAP00000023463
Zmp:0000000662.
    
 
 0.435
ENSCHAP00000033216
Ring finger protein 145b.
    
 
 0.435
ENSCHAP00000014943
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
    
 
 0.433
rnf139
Ring finger protein 139.
    
 
 0.430
ENSCHAP00000060806
Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase.
    
 
 0.430
LOC105906676
Uncharacterized LOC105906676.
   
 
 0.403
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.