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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
npc2NPC intracellular cholesterol transporter 2. (149 aa)    
Predicted Functional Partners:
ENSCHAP00000049895
Niemann-Pick disease, type C1.
   
 0.992
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.989
scap
SREBF chaperone.
   
 0.964
ENSCHAP00000032703
annotation not available
     
 0.639
ENSCHAP00000049395
annotation not available
     
 0.639
ENSCHAP00000049489
annotation not available
     
 0.639
LOC105909579
Apolipoprotein B-100-like.
     
 0.639
apob
Apolipoprotein B.
     
 0.639
ENSCHAP00000045522
Nudix (nucleoside diphosphate linked moiety X)-type motif 19.
    
   0.611
ENSCHAP00000029602
Vitellogenin 3, phosvitinless.
     
 0.601
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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