STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000003889MDM4 regulator of p53. (505 aa)    
Predicted Functional Partners:
ENSCHAP00000010851
MDM2 proto-oncogene.
    
0.999
ENSCHAP00000039408
Tumor protein p53.
   
 0.992
ENSCHAP00000042143
annotation not available
   
 0.990
ENSCHAP00000039357
Tumor protein p53.
   
 0.985
rps27a
Ribosomal protein S27a.
    
 0.976
ENSCHAP00000062650
Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).
   
 0.974
rb1
RB transcriptional corepressor 1.
    
 0.965
usp7
Ubiquitin specific peptidase 7.
    
 0.961
ENSCHAP00000030291
Ubiquitin B.
    
 0.953
rpl11
Ribosomal protein L11.
    
 
 0.927
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.