STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000003924Tumor protein p63. (633 aa)    
Predicted Functional Partners:
ENSCHAP00000010851
MDM2 proto-oncogene.
    
 0.962
ENSCHAP00000055703
WW domain containing transcription regulator 1.
    
 0.945
ENSCHAP00000035355
ATM serine/threonine kinase.
   
 0.934
chek2
Checkpoint kinase 2.
    
 0.926
ENSCHAP00000038241
ATR serine/threonine kinase.
    
 0.923
chek1
Checkpoint kinase 1.
    
 0.909
ENSCHAP00000024514
WRN RecQ like helicase.
    
 0.907
ENSCHAP00000038384
annotation not available
    
 0.897
ENSCHAP00000003889
MDM4 regulator of p53.
    
 0.893
ENSCHAP00000052732
Itchy E3 ubiquitin protein ligase a.
    
 0.862
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.