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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000004463annotation not available (180 aa)    
Predicted Functional Partners:
LOC105909873
Tumor necrosis factor receptor superfamily member 1B-like.
     
 0.827
ENSCHAP00000000306
Pleckstrin homology domain containing, family G (with RhoGef domain) member 5b.
    
 0.739
ENSCHAP00000023227
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.739
ENSCHAP00000026053
Pleckstrin homology domain containing, family G (with RhoGef domain) member 5a.
    
 0.739
ENSCHAP00000029528
annotation not available
    
 0.739
ENSCHAP00000046529
Pleckstrin homology domain containing, family G (with RhoGef domain) member 7.
    
 0.739
ENSCHAP00000000392
annotation not available
   
 0.721
ENSCHAP00000000448
annotation not available
   
 0.721
TNFRSF11B
TNF receptor superfamily member 11b.
   
 0.721
TNFRSF6B
TNF receptor superfamily member 6b.
   
 0.721
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.