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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000005008Complement component 8, beta polypeptide. (644 aa)    
Predicted Functional Partners:
ENSCHAP00000016490
Intersectin 2b.
   
 0.989
ENSCHAP00000057857
Intersectin 2a.
   
 0.989
ENSCHAP00000046920
Complement component 9.
   
0.954
C8A
Complement component C8 alpha chain-like.
  
0.945
ENSCHAP00000039421
Complement component 5.
   
 0.944
ENSCHAP00000030988
Complement component 6.
   
 
 
0.935
LOC105889048
Apoptosis regulator BAX-like.
   
 
  0.924
ENSCHAP00000018309
Complement component 8, gamma polypeptide.
   
 0.922
ENSCHAP00000030296
BCL2 associated X, apoptosis regulator a.
   
 
  0.914
plekha7
Pleckstrin homology domain containing A7.
    
  0.897
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.