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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000005322Patched domain containing 4. (913 aa)    
Predicted Functional Partners:
npc2
NPC intracellular cholesterol transporter 2.
   
 
  0.508
zic1
Zic family member 1.
      
 0.444
ENSCHAP00000009844
Synaptic Ras GTPase activating protein 1b.
      
 0.431
ENSCHAP00000020507
FIC domain containing.
      
 0.414
ENSCHAP00000029214
Recombination activating gene 2.
      
 0.404
vps26b
VPS26, retromer complex component B.
    
 
 0.402
ripk4
Receptor interacting serine/threonine kinase 4.
      
 0.400
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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