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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000005390General transcription factor IIH, polypeptide 5. (71 aa)    
Predicted Functional Partners:
ENSCHAP00000002381
Excision repair cross-complementation group 3.
   
 0.999
ENSCHAP00000026594
General transcription factor IIH, polypeptide 3.
    
 0.998
gtf2h1
General transcription factor IIH subunit 1.
    
 0.998
ckm
ERCC excision repair 2, TFIIH core complex helicase subunit.
    
 0.997
ccnh
Cyclin H.
    
 0.997
LOC105889985
General transcription factor IIH subunit 2-like.
    
 0.997
ENSCHAP00000036029
annotation not available
    
 0.994
ENSCHAP00000037448
General transcription factor IIH, polypeptide 4.
    
 0.994
mnat1
MNAT1 component of CDK activating kinase.
    
 0.993
gtf2f1
General transcription factor IIF subunit 1.
    
 0.992
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.