close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000006457Insulin-like growth factor binding protein 2a. (277 aa)    
Predicted Functional Partners:
LOC105904486
Insulin-like growth factor II.
   
 0.874
LOC105908126
Insulin-like growth factor II.
   
 0.874
igf1
Insulin like growth factor 1.
     
 0.655
igfals
Insulin like growth factor binding protein acid labile subunit.
   
 0.614
LOC105905660
Leucine-rich repeat-containing protein 17-like.
   
 0.562
ENSCHAP00000039491
Tubulin, gamma complex associated protein 5.
      
 0.531
nipa1
NIPA magnesium transporter 1.
      
 0.529
ENSCHAP00000057401
Preproinsulin.
      
 0.524
ENSCHAP00000012299
annotation not available
      
 0.521
ENSCHAP00000011045
Pregnancy-associated plasma protein A, pappalysin 1a.
    
 0.512
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (22%) [HD]