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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000006624ABI family, member 3a. (441 aa)    
Predicted Functional Partners:
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
 0.986
cyfip1
Cytoplasmic FMR1 interacting protein 1.
    
 0.984
ENSCHAP00000051624
Cytoplasmic FMR1 interacting protein 2.
    
 0.977
nckap1
NCK associated protein 1.
   
 0.956
nckap1l
NCK associated protein 1 like.
   
 0.956
ENSCHAP00000049306
WASP family member 1.
    
 0.933
ENSCHAP00000060048
WASP family member 2.
    
 0.933
ENSCHAP00000021566
Zgc:109889.
    
 0.890
ENSCHAP00000022356
Si:ch73-362m14.4.
    
 0.890
wasf3
WASP family member 3.
    
 0.890
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.