close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
myd88MYD88 innate immune signal transduction adaptor. (286 aa)    
Predicted Functional Partners:
ENSCHAP00000040398
Interleukin-1 receptor-associated kinase 4.
   
 0.997
ENSCHAP00000007881
Toll-like receptor 4b, duplicate a.
   
 0.996
ENSCHAP00000048013
Mitogen-activated protein kinase kinase kinase 7.
   
 0.996
ENSCHAP00000017131
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
    
 0.991
ENSCHAP00000033351
TNF receptor-associated factor 6.
   
 0.984
TRAF6
TNF receptor-associated factor 6-like.
   
 0.984
TLR2
Toll like receptor 2.
   
 0.963
fadd
Fas associated via death domain.
   
 0.958
ENSCHAP00000061091
Toll-like receptor 7.
   
 0.957
LOC105898070
Toll-like receptor 8.
   
 0.957
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (20%) [HD]