close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB4Phospholipase C beta 4. (1103 aa)    
Predicted Functional Partners:
LOC105889474
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.916
ENSCHAP00000052663
annotation not available
    
 0.914
ENSCHAP00000053577
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.910
ENSCHAP00000016183
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.
    
 0.901
LOC105912811
Guanine nucleotide-binding protein subunit alpha-14-like.
    
 0.901
ENSCHAP00000054563
Inositol 1,4,5-trisphosphate receptor, type 2.
    
 0.864
DGKQ
Diacylglycerol kinase theta.
     
 0.862
LOC105897337
Guanine nucleotide-binding protein G(k) subunit alpha.
   
 0.858
GNAO1
G protein subunit alpha o1.
   
 0.851
ENSCHAP00000029531
Inositol polyphosphate-5-phosphatase L.
   
 
 0.850
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.