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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crlf1Cytokine receptor like factor 1. (413 aa)    
Predicted Functional Partners:
ENSCHAP00000001459
Cardiotrophin-like cytokine factor 1.
    
 0.926
LOC105898658
Prolactin-like.
    
 0.861
ENSCHAP00000036492
annotation not available
    
 0.861
ENSCHAP00000042505
annotation not available
    
 0.861
ENSCHAP00000000589
Interleukin 11a.
     
 0.790
ENSCHAP00000031995
Leptin a.
     
 0.790
ENSCHAP00000016397
Somatolactin alpha.
   
 0.781
ENSCHAP00000036345
Growth hormone 1.
   
 0.781
ENSCHAP00000036531
annotation not available
   
 0.781
ENSCHAP00000050687
annotation not available
     
 0.768
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.