ENSCHAP00000007084 protein (Clupea harengus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSCHAP00000007084

annotation not available (1046 aa)

Predicted Functional Partners:

ENSCHAP00000008710

0.993

ENSCHAP00000012123

0.993

taf11

0.993

ENSCHAP00000014898

0.993

LOC105893216

0.993

taf6

0.993

taf8

0.992

taf6l

0.987

taf10

0.976

taf13

0.976

Your Current Organism:

Clupea harengus

NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCHAP00000007084	ENSCHAP00000008710	ENSCHAP00000007084	ENSCHAP00000008710	annotation not available	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.993
ENSCHAP00000007084	ENSCHAP00000012123	ENSCHAP00000007084	ENSCHAP00000012123	annotation not available	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.993
ENSCHAP00000007084	ENSCHAP00000014898	ENSCHAP00000007084	ENSCHAP00000014898	annotation not available	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.993
ENSCHAP00000007084	LOC105893216	ENSCHAP00000007084	ENSCHAP00000038058	annotation not available	Transcription initiation factor TFIID subunit 1-like.	0.993
ENSCHAP00000007084	taf10	ENSCHAP00000007084	ENSCHAP00000003532	annotation not available	TATA-box binding protein associated factor 10.	0.976
ENSCHAP00000007084	taf11	ENSCHAP00000007084	ENSCHAP00000013158	annotation not available	TATA-box binding protein associated factor 11.	0.993
ENSCHAP00000007084	taf13	ENSCHAP00000007084	ENSCHAP00000040484	annotation not available	TATA-box binding protein associated factor 13.	0.976
ENSCHAP00000007084	taf6	ENSCHAP00000007084	ENSCHAP00000040464	annotation not available	TATA-box binding protein associated factor 6.	0.993
ENSCHAP00000007084	taf6l	ENSCHAP00000007084	ENSCHAP00000026018	annotation not available	TATA-box binding protein associated factor 6 like.	0.987
ENSCHAP00000007084	taf8	ENSCHAP00000007084	ENSCHAP00000002852	annotation not available	TATA-box binding protein associated factor 8.	0.992
ENSCHAP00000008710	ENSCHAP00000007084	ENSCHAP00000008710	ENSCHAP00000007084	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	annotation not available	0.993
ENSCHAP00000008710	ENSCHAP00000012123	ENSCHAP00000008710	ENSCHAP00000012123	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
ENSCHAP00000008710	ENSCHAP00000014898	ENSCHAP00000008710	ENSCHAP00000014898	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
ENSCHAP00000008710	LOC105893216	ENSCHAP00000008710	ENSCHAP00000038058	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Transcription initiation factor TFIID subunit 1-like.	0.999
ENSCHAP00000008710	taf10	ENSCHAP00000008710	ENSCHAP00000003532	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 10.	0.999
ENSCHAP00000008710	taf11	ENSCHAP00000008710	ENSCHAP00000013158	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 11.	0.999
ENSCHAP00000008710	taf13	ENSCHAP00000008710	ENSCHAP00000040484	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 13.	0.999
ENSCHAP00000008710	taf6	ENSCHAP00000008710	ENSCHAP00000040464	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 6.	0.999
ENSCHAP00000008710	taf6l	ENSCHAP00000008710	ENSCHAP00000026018	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 6 like.	0.997
ENSCHAP00000008710	taf8	ENSCHAP00000008710	ENSCHAP00000002852	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 8.	0.999

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.794

expected number of edges:

13

PPI enrichment p-value:

0.0158

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022900

Electron transport chain

6 of 86

1.45

1.61

4.69e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004556

Alpha-amylase activity

2 of 2

2.61

0.83

0.0314

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:31379757

(2019) Hydrostatic Pressure Helps to Cultivate an Original Anaerobic Bacterium From the Atlantis Massif Subseafloor (IODP Expedition 357): Petrocella atlantisensis gen. nov. sp. nov.

3 of 3

2.61

1.97

0.00023

PMID:36303868

(2022) White common bean extract remodels the gut microbiota and ameliorates type 2 diabetes and its complications: A randomized double-blinded placebo-controlled trial.

2 of 2

2.61

0.97

0.0176

PMID:30100182

(2018) Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen.

2 of 3

2.43

0.94

0.0195

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3649

This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins., and Electron transport

6 of 10

2.39

4.69

3.40e-10

CL:3652

Mixed, incl. RnfC Barrel sandwich hybrid domain, and This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins.

5 of 5

2.61

4.39

4.00e-09

CL:5617

Alpha-amylase domain, and Glycosyl hydrolases family 31

2 of 5

2.21

0.83

0.0296

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0249

Electron transport

6 of 31

1.9

3.23

2.43e-08

KW-1278

Translocase

5 of 43

1.67

2.13

6.56e-06

KW-0106

Calcium

2 of 8

2.01

1.0

0.0127

KW-0997

Cell inner membrane

5 of 162

1.1

0.87

0.0023

KW-0004

4Fe-4S

3 of 58

1.32

0.78

0.0160

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00642

Alpha-amylase domain

2 of 4

2.31

1.04

0.0118

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (16%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About