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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000007762SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (466 aa)    
Predicted Functional Partners:
ENSCHAP00000016397
Somatolactin alpha.
    
 0.710
ENSCHAP00000036345
Growth hormone 1.
    
 0.710
ENSCHAP00000036531
annotation not available
    
 0.710
ENSCHAP00000031995
Leptin a.
     
 0.607
ENSCHAP00000042950
Interleukin 2 receptor, beta.
   
 
  0.593
ENSCHAP00000052300
Interleukin 7 receptor.
   
 
  0.591
ENSCHAP00000050687
annotation not available
     
 0.586
LOC105898658
Prolactin-like.
     
 0.534
ENSCHAP00000036492
annotation not available
     
 0.534
ENSCHAP00000042505
annotation not available
     
 0.534
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.