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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000008286annotation not available (813 aa)    
Predicted Functional Partners:
ENSCHAP00000051061
Interferon regulatory factor 9.
   
 0.934
JAK1
Tyrosine-protein kinase JAK1-like.
   
 0.930
ENSCHAP00000032182
Tyrosine kinase 2.
   
 0.929
jak3
Janus kinase 3.
   
 0.928
ENSCHAP00000022453
Janus kinase 2a.
   
 0.927
ENSCHAP00000025501
CREB binding protein a.
    
 0.889
ENSCHAP00000036810
Erb-b2 receptor tyrosine kinase 4a.
    
 0.869
erbb4
Erb-b2 receptor tyrosine kinase 4.
    
 0.869
ENSCHAP00000020098
Protein inhibitor of activated STAT, 4b.
    
 0.861
ENSCHAP00000034698
annotation not available
    
 0.851
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.