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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
jak3Janus kinase 3. (1102 aa)    
Predicted Functional Partners:
ENSCHAP00000053040
Signal transducer and activator of transcription 6, interleukin-4 induced.
   
 0.947
ENSCHAP00000007910
Signal transducer and activator of transcription 2.
   
 0.946
ENSCHAP00000052302
Signal transducer and activator of transcription 1a.
   
 0.945
ENSCHAP00000028273
Signal transducer and activator of transcription 5b.
   
 0.939
ENSCHAP00000008527
Signal transducer and activator of transcription 3 (acute-phase response factor).
   
 0.931
ENSCHAP00000022612
Signal transducer and activator of transcription 4.
   
 0.931
ENSCHAP00000015292
annotation not available
    
 0.930
ENSCHAP00000008286
annotation not available
   
 0.928
ENSCHAP00000013182
Leptin receptor.
    
 0.901
ENSCHAP00000038399
Colony stimulating factor 3 receptor (granulocyte).
   
 0.888
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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