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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000009040Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a. (464 aa)    
Predicted Functional Partners:
ENSCHAP00000047446
annotation not available
      
 0.522
ENSCHAP00000007314
Angiotensin I converting enzyme 2.
    
 0.464
ace
Angiotensin I converting enzyme.
    
 0.464
ENSCHAP00000050679
annotation not available
    
 0.464
ENSCHAP00000051340
annotation not available
    
 0.464
ENSCHAP00000051345
Si:dkey-194e6.1.
    
 0.464
HGFAC
HGF activator.
   
  0.458
ENSCHAP00000038619
annotation not available
   
  0.458
HABP2
Hyaluronan binding protein 2.
   
  0.458
ENSCHAP00000018534
N-ethylmaleimide-sensitive factor a.
   
  0.422
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.