close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000009266Mitogen-activated protein kinase kinase kinase kinase 5. (876 aa)    
Predicted Functional Partners:
traf2
TNF receptor associated factor 2.
    
  0.720
ENSCHAP00000055060
Mitogen-activated protein kinase kinase kinase kinase 2.
  
  
 
0.704
ENSCHAP00000003476
Tnf receptor-associated factor 2a.
    
  0.610
LOC105902465
TNF receptor-associated factor 2-like.
    
  0.610
ENSCHAP00000007513
GRB2 related adaptor protein 2a.
    
 
 0.592
ENSCHAP00000008521
GRB2 related adaptor protein 2b.
    
 
 0.592
ENSCHAP00000000884
annotation not available
   
 
0.583
LOC105890180
Mitogen-activated protein kinase kinase kinase 3-like.
   
 
0.583
ENSCHAP00000019911
Mitogen-activated protein kinase kinase kinase 3.
   
 
0.583
ENSCHAP00000045645
Mitogen-activated protein kinase kinase kinase 19.
   
 
0.583
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
Server load: low (22%) [HD]