close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000009954Integrin alpha 4. (1027 aa)    
Predicted Functional Partners:
itgb8
Integrin subunit beta 8.
    
 0.973
ENSCHAP00000010301
Integrin, beta 1b.
   
 0.964
itgb5
Integrin subunit beta 5.
   
 0.960
itgb6
Integrin subunit beta 6.
   
 0.960
ENSCHAP00000023060
Integrin, beta 4.
   
 0.960
ENSCHAP00000042663
Integrin, alpha 2b.
  
 
0.938
lamc1
Laminin subunit gamma 1.
    
 0.931
ITGA7
Integrin subunit alpha 7.
  
  
0.930
ENSCHAP00000015849
Integrin, alpha 10.
   
 
0.924
ENSCHAP00000054227
Vascular cell adhesion molecule 1b.
   
 0.922
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.