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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCHAP00000010400Leucine-zipper-like transcription regulator 1. (799 aa)    
Predicted Functional Partners:
klhl22
Kelch like family member 22.
   
0.934
ENSCHAP00000027667
Cullin 3a.
    
 0.921
ENSCHAP00000001317
Kelch-like family member 24a.
    
0.919
ENSCHAP00000047744
annotation not available
    
  0.918
ENSCHAP00000062014
Kelch-like family member 8.
    
  0.918
ENSCHAP00000001115
Kelch-like family member 7.
    
  0.917
klhl21
Kelch like family member 21.
    
 
0.897
klhl13
Kelch like family member 13.
    
 
0.889
spop
Speckle type BTB/POZ protein.
   
 
0.829
LOC105911847
Speckle-type POZ protein-like B.
   
 
0.829
Your Current Organism:
Clupea harengus
NCBI taxonomy Id: 7950
Other names: Atlantic herring, C. harengus, Clupea harengus harengus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.